Will James Cook play against the Miami Dolphins tonight? Latest injury update on the popular Buffalo Bills’ player | NFL News

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Will James Cook play against the Miami Dolphins tonight? Latest injury update on the popular Buffalo Bills' player
Bills’ James Cook will play against Dolphins (Image via: Getty Images)

The Buffalo Bills are gearing up for a pivotal Week 3 Thursday Night Football clash against the Miami Dolphins, and one burning question for fans and fantasy football managers alike is the status of star running back James Cook. With Buffalo off to a red-hot 2-0 start and Miami still searching for their first win of the 2025 NFL season, Cook’s presence could be the difference-maker under the primetime lights in Orchard Park.

Is James Cook playing for the Buffalo Bills in Thursday Night Football of Week 3?

Yes, James Cook is playing tonight as the Buffalo Bills face the Miami Dolphins in Week 3 of Thursday Night Football. The star running back has not been listed with any injury designation ahead of kickoff, which is a major relief for Bills fans and fantasy football managers alike. Cook has been a key contributor to Buffalo’s 2-0 start this season, showcasing his explosive speed and ability to create plays out of the backfield. Cook’s availability also strengthens Buffalo’s ground attack, which has provided much-needed balance to Josh Allen’s aerial game. Facing a Miami team that has yet to secure a win this season, Cook’s role will be crucial in ensuring the Bills continue their dominant start to the 2025 NFL season.

Week 3 Fantasy Football RB Rankings (Top 40)

Buffalo Bills key players to watch in Week 3 Thursday Night Football

Buffalo’s offense has been firing on all cylinders through the first two weeks of the season. Quarterback Josh Allen has been at the center of it all, throwing for 542 yards with two touchdowns, no interceptions, and completing over 66% of his passes. His poise and accuracy have kept the Bills in control of every matchup so far.Alongside him, James Cook has been equally impressive on the ground. The dynamic running back has already totaled 176 rushing yards and three touchdowns, averaging a strong 5.2 yards per carry. His ability to break tackles and extend plays has added a dangerous edge to Buffalo’s running game.Rookie wideout Keon Coleman is also emerging as a reliable target. With 11 catches for 138 yards and a touchdown, he’s quickly proving to be an important weapon in Allen’s arsenal. Together, this trio has powered Buffalo’s offense, making the Bills one of the most balanced and threatening teams in the league heading into Week 3.

Buffalo Bills vs. Miami Dolphins: When and Where to watch Thursday Night Football

Date: Thursday, Sept. 18, 2025Kickoff Time: 8:15 p.m. ETLocation: Highmark Stadium, Orchard Park, NYStreaming: Prime VideoAlso Read: Patrick Mahomes’ birthday proves lucky charm for Chiefs as Xavier Worthy and Jalen Royals back in actionThe highly anticipated Week 3 Thursday Night Football matchup brings together two AFC East rivals at Highmark Stadium. The betting odds reflect Buffalo’s strong position, with analysts predicting a comfortable win for the Bills. As Thursday Night Football takes center stage in Week 3, all eyes will be on James Cook and the Buffalo Bills to see if they can extend their unbeaten run and further cement themselves as early favorites in the AFC.





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